Methods for preparation of heterobifunctional nitroxides: α,β-unsaturated ketones, β-ketoesters, cyano-nitro-derivatives
نویسندگان
چکیده
منابع مشابه
Efficient synthesis of β’-amino-α,β-unsaturated ketones
A general and simple procedure to access chiral β'-amino-α,β-enones, in seven steps, from an α,β unsaturated ester has been described. The use of a Horner-Wadsworth-Emmons reaction as a key step for generating the β'-amino-α,β-enones, permits access to a range of substrates under mild conditions and in moderate to high yield.
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Efficient asymmetric bio-epoxidation of electron-deficient α,β-unsaturated ketones was realized via a tandem reduction-epoxidation-dehydrogenation cascade, which proceeds in a switchable manner to afford either chiral epoxy ketones or allylic epoxy alcohols with up to >99% yield and >99%ee.
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Uma série de cetonas e ésteres α,β-insaturados β-amino ésteres, 4a-h e 6a-d, derivados de α-amino ácidos foi obtida a partir dos cloridratos dos α-amino ésteres 2a-d e dos compostos 1,3-dicarbonílicos 3a,b e 5 em presença de trietilamina. Estes compostos foram preparados empregando energia de microondas, sem uso de solvente, utilizando como suporte sólido K-10 ou KSF e também foram efetuadas re...
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The reactions of selected α,β-unsaturated steroidal ketones with Lawesson’s reagent (LR) in CH2Cl2 and toluene under the standard reaction conditions and with a combination of phosphorus pentasulfide with hexamethyldisiloxane (P4S10/HMDO) in 1,2dichlorobenzene (ODCB) under microwave irradiation were investigated and for this purpose several cholestane, androstane and pregnane carbonyl derivativ...
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1982
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v82-208